Description
How it works
Clobetasol propionate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.
Usage And Safety
Dosage
Adults : Apply sparingly once or twice daily for max four wk, then review. Children : Same as adult but review weekly. OR As directed by your physician.
Side Effects
Common (may affect up to 1 in 10 people)• a feeling of burning, pain, irritation or itching where the ointment is applied.Uncommon (may affect up to 1 in 100 people)• skin thinning, stretch marks may develop. • blood vessels under the surface of your skin may become more noticeable. Very Rare (may affect up to 1 in 10,000 people)Use of Dermovate for a long period of time, or use under an airtight dressing, may cause the following symptoms:• increased weight • moon face, rounding of the face • obesity • skin thinning • skin wrinkling • skin dryness • changes to the colour of your skin • increased body hair • hair loss/lack of hair growth/damaged looking hair.
